Determination of evodiamine and rutacarpine in zhuyu hewei zhitong capsules by HPLC / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 871-873, 2011.
Article
de Zh
| WPRIM
| ID: wpr-247370
Bibliothèque responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To develop a HPLC method for the determination of evodiamine and rutacarpine in Zhuyu Hewei Zhitong capsules.</p><p><b>METHOD</b>The separation was performed at 30 degrees C on an Eclipse XDB-C18 column (4.6 mm x 150 mm, 5 microm) eluted with the mobile phase consisted of acetonitrile-water(45:55). The detection wavelength was 250 nm.</p><p><b>RESULTS</b>The standard curve for evodiamine is linear in the range of 0.0510-0.560 microg, the average recovery was 97.5% (RSD 1.0%). The standard curve for rutacarpine is linear in the range of 0.0508-0.559 microg, the average recovery was 98.7% (RSD 1.5%).</p><p><b>CONCLUSION</b>The method is specific, accurate and stable. It can be used for detemination of evodiamine and rutacarpine in Zhuyu Hewei Zhitong capsules.</p>
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Contrôle de qualité
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Quinazolines
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Normes de référence
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Capsules
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Médicaments issus de plantes chinoises
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Modèles linéaires
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Chimie
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Reproductibilité des résultats
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Chromatographie en phase liquide à haute performance
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Alcaloïdes
Type d'étude:
Prognostic_studies
langue:
Zh
Texte intégral:
China Journal of Chinese Materia Medica
Année:
2011
Type:
Article