Prognostic Impact of Cerebral Small Vessel Disease on Stroke Outcome / 대한뇌졸중학회지
Journal of Stroke
;
: 101-110, 2015.
Article
Dans Anglais
| WPRIM
| ID: wpr-24751
ABSTRACT
Cerebral small vessel disease (SVD), which includes white matter hyperintensities (WMHs), silent brain infarction (SBI), and cerebral microbleeds (CMBs), develops in a conjunction of cumulated injuries to cerebral microvascular beds, increased permeability of blood-brain barriers, and chronic oligemia. SVD is easily detected by routine neuroimaging modalities such as brain computed tomography or magnetic resonance imaging. Research has revealed that the presence of SVD markers may increase the risk of future vascular events as well as deteriorate functional recovery and neurocognitive trajectories after stroke, and such an association could also be applied to hemorrhagic stroke survivors. Currently, the specific mechanistic processes leading to the development and manifestation of SVD risk factors are unknown, and further studies with novel methodological tools are warranted. In this review, recent studies regarding the prognostic impact of WMHs, SBI, and CMBs on stroke survivors and briefly summarize the pathophysiological concepts underlying the manifestation of cerebral SVD.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Perméabilité
/
Pronostic
/
Encéphale
/
Imagerie par résonance magnétique
/
Barrière hémato-encéphalique
/
Facteurs de risque
/
Survivants
/
Accident vasculaire cérébral
/
Infarctus encéphalique
/
Maladies des petits vaisseaux cérébraux
Type d'étude:
Etude d'étiologie
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Journal of Stroke
Année:
2015
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS