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Y-chromosome-specific microsatellite variation in Li ethnic groups of Hainan Island, China / 中华医学遗传学杂志
Chinese Journal of Medical Genetics ; (6): 46-48, 2003.
Article Dans Chinois | WPRIM | ID: wpr-248503
ABSTRACT
<p><b>OBJECTIVE</b>The study was conducted to reveal the distribution of genetic polymorphism of four Y chromosome specific short tandem repeat (Y-specific STR) loci in Li ethnic groups in Hainan Island, China.</p><p><b>METHODS</b>Four tetranucleotide STR loci were simultaneously amplified with fluorescently labeled primers, and genotypes were determined with an automated DNA sequencer.</p><p><b>RESULTS</b>Among 230 unrelated males, the alleles at the four Y-specific STR loci were composed of some complex repeat structure. 4,5,4,5 alleles were observed in loci DYS3891, DYS390, DYS391, DYS393 respectively. A set of human allele ladders for the typing of the four Y-specific STRs was obtained in Li ethnic population. Gene diversity index (D) and haplotype diversity data were estimated for the four Y-STRs.</p><p><b>CONCLUSION</b>The preliminary study indicates a reference population for detecting male migration events and should be useful in population genetics and forensic applications.</p>
Sujets)
Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Variation génétique / Haplotypes / ADN / Chimie / Chine / Analyse de séquence d&apos;ADN / Répétitions microsatellites / Chromosomes Y humains / Fréquence d&apos;allèle / Génétique Limites du sujet: Humains / Mâle Pays comme sujet: Asie langue: Chinois Texte intégral: Chinese Journal of Medical Genetics Année: 2003 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Variation génétique / Haplotypes / ADN / Chimie / Chine / Analyse de séquence d&apos;ADN / Répétitions microsatellites / Chromosomes Y humains / Fréquence d&apos;allèle / Génétique Limites du sujet: Humains / Mâle Pays comme sujet: Asie langue: Chinois Texte intégral: Chinese Journal of Medical Genetics Année: 2003 Type: Article