Y-chromosome-specific microsatellite variation in Li ethnic groups of Hainan Island, China / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 46-48, 2003.
Article
Dans Chinois
| WPRIM
| ID: wpr-248503
ABSTRACT
<p><b>OBJECTIVE</b>The study was conducted to reveal the distribution of genetic polymorphism of four Y chromosome specific short tandem repeat (Y-specific STR) loci in Li ethnic groups in Hainan Island, China.</p><p><b>METHODS</b>Four tetranucleotide STR loci were simultaneously amplified with fluorescently labeled primers, and genotypes were determined with an automated DNA sequencer.</p><p><b>RESULTS</b>Among 230 unrelated males, the alleles at the four Y-specific STR loci were composed of some complex repeat structure. 4,5,4,5 alleles were observed in loci DYS3891, DYS390, DYS391, DYS393 respectively. A set of human allele ladders for the typing of the four Y-specific STRs was obtained in Li ethnic population. Gene diversity index (D) and haplotype diversity data were estimated for the four Y-STRs.</p><p><b>CONCLUSION</b>The preliminary study indicates a reference population for detecting male migration events and should be useful in population genetics and forensic applications.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Variation génétique
/
Haplotypes
/
ADN
/
Chimie
/
Chine
/
Analyse de séquence d'ADN
/
Répétitions microsatellites
/
Chromosomes Y humains
/
Fréquence d'allèle
/
Génétique
Limites du sujet:
Humains
/
Mâle
Pays comme sujet:
Asie
langue:
Chinois
Texte intégral:
Chinese Journal of Medical Genetics
Année:
2003
Type:
Article
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