Variations of hepatitis B virus infection epidemic pattern after long-term HBV vaccine immunization / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
; (6): 253-255, 2007.
Article
de Zh
| WPRIM
| ID: wpr-248787
Bibliothèque responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the epidemic pattern and trend of HBV infection in the area where the people had been immunized by HBV vaccine for 20 years.</p><p><b>METHODS</b>The whole sampling method was applied in combination with cross-sectional investigation. Blood samples were taken from every member of families. Markers of HBV infection were determined by using solid-phase radioimmunoassay (SPRIA).</p><p><b>RESULTS</b>(1) The average HBsAg positive rate was 7.5%. The positive rate of markers for HBV infection of 0-19 years old subjects were lower than those of > or = 20 years old subjects. (2) The positive rate of HBsAg of 0-19 years old subjects in 1985 was higher than that in 2005. The anti-HBs positive rate in 1985 stemmed to be higher with age. It was 12.4% in 1- age group to 53.8% in >60 years age group. While the result of 2005 showed that the anti-HBs positive rate of 0-19 years old subjects dropped with age. The anti-HBc positive rate in 1985 also tended to be higher with age. But the result of 2005 showed that the rate of 0-19 years old subjects was just 1.4% to 16.8%.</p><p><b>CONCLUSION</b>The epidemic patterns of HBV infection have had significant variations in the target population. HBV vaccine immunization has obtained excellent efficacy.</p>
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Facteurs temps
/
Sang
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Études séroépidémiologiques
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Chine
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Épidémiologie
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Études transversales
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Immunisation
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Résultat thérapeutique
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Vaccins anti-hépatite B
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Utilisations thérapeutiques
Type d'étude:
Observational_studies
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Prevalence_studies
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Risk_factors_studies
Limites du sujet:
Adolescent
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Adult
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Aged
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Child
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Child, preschool
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Female
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Humans
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Infant
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Male
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Newborn
Pays comme sujet:
Asia
langue:
Zh
Texte intégral:
Chinese Journal of Experimental and Clinical Virology
Année:
2007
Type:
Article