Evaluation of a heart-type fatty acid-binding protein detection kit for diagnosis of acute coronary syndrome / 南方医科大学学报
Journal of Southern Medical University
;
(12): 901-903, 2014.
Article
Dans Chinois
| WPRIM
| ID: wpr-249336
ABSTRACT
<p><b>OBJECTIVE</b>To evaluation the performance of a heart-type fatty acid-binding protein (H-FABP) ELISA detection kit in the clinical diagnosis of acute coronary syndrome (ACS).</p><p><b>METHODS</b>Plasma or serum samples from 160 suspected ACS patients hospitalized in General Hospital of PLA were examined using Lanzhou H-FABP reagent kit and Holland H-FABP kit. Correlation of the two kits was evaluated and Kappa test was used to examine the consistency of the results of the two products.</p><p><b>RESULTS</b>The sensitivity of H-FABP diagnosis of ACS detection Lanzhou kit was 91.8%, the specificity was 88.7%, and the total diagnostic rate was 90.42%. The sensitivity of H-FABP diagnosis of ACS detection Holland kit was 90.3%, the specificity was 86.8%, and the total diagnostic rate was 88.75%. The test results showed that two products yielded comparable results (P=0.668, >0.05) with a good consistency (Kappa=0.726, P<0.01).</p><p><b>CONCLUSIONS</b>H-FABP ELISA detection kit produccted by LanZhou biological research institute has a good correlation with H-FABP detection kit produced by HBT company of Holland and has the potential for clinical application.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Trousses de réactifs pour diagnostic
/
Sang
/
Test ELISA
/
Marqueurs biologiques
/
Reproductibilité des résultats
/
Sensibilité et spécificité
/
Diagnostic
/
Protéines de liaison aux acides gras
/
Syndrome coronarien aigu
/
Protéine-3 liant les acides gras
Type d'étude:
Etude diagnostique
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Journal of Southern Medical University
Année:
2014
Type:
Article
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