A Case of Palmar Filiform Hyperkeratosis / 대한피부과학회지

ABSTRACT

Palmar filiform hyperkeratosis is characterized by multiple, tiny, keratotic projections on the palms. This disease has been associated with various underlying benign or malignant diseases. We present 69 year-old-man with 8-year history of palmar filiform hyperkeratosis. After development of skin lesions, he was diagnosed as having rheumatoid arthritis, hypertension, chronic renal failure, multiple renal and hepatic cysts, and multiple adenomas in the stomach and colon, in turn. Histopathologic examination revealed a compact parakeratotic column on an absent or thin granular layer. Treatment with 15% salicylic acid ointment under occlusion was partially effective.