Progress on genetic basis of primary aldosteronism / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 612-618, 2014.
Article
Dans Chinois
| WPRIM
| ID: wpr-251655
ABSTRACT
It has been proven that familial aldosteronism type I is related to 11-beta hydroxylase (CYP11B1)/aldosterone synthase (CYP11B2) chimeric genes. In recent years, accumulated evidences indicate that the genetic basis of primary aldosteronism may involve chromosome 7p22 candidate genes, polymorphisms of CYP11B1 and CYP11B2 genes, mutations of ion channel- related KCNJ5, ATP1A1, CACNA1D genes. The article reviews the progress on genetic basis of primary aldosteronism.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Polymorphisme génétique
/
Steroid 11-beta-hydroxylase
/
Cytochrome P-450 CYP11B2
/
Génétique
/
Hyperaldostéronisme
/
Mutation
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Journal of Zhejiang University. Medical sciences
Année:
2014
Type:
Article
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