Diffusion weighted imaging combined with dynamic contrast enhanced magnetic resonance imaging in monitoring therapeutic efficacy for hepatocellular carcinoma after transcatheter arterial chemoembolization / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 77-82, 2014.
Article
Dans Chinois
| WPRIM
| ID: wpr-251718
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the diagnostic value of diffusion weighted imaging (DWI) combined with dynamic contrast-enhanced (DCE) MRI in monitoring the efficacy for hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE).</p><p><b>METHODS</b>MRI and CT scan were performed 4-6 weeks after TACE in 31 patients.With digital signature algorithm (DSA) examination as the reference standard, the value in detection of the residue and recurrence of HCC was compared between MRI and CT results.</p><p><b>RESULTS</b>Seventy-three lesions were detected in 31 patients. Fourteen lesions confirmed by DSA had no tumor staining, and 59 lesions had tumor staining. Diagnostic sensitivity and specificity of DCE-CT were 78.0% and 85.7%, respectively; while those of DWI combined with DCE-MRI were 100% and 92.9% (P<0.001).</p><p><b>CONCLUSION</b>DWI combined with DCE-MRI is more effective than DCE-CT in detecting the residue and recurrence of HCC after TACE.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Thérapeutique
/
Tomodensitométrie
/
Sensibilité et spécificité
/
Chimioembolisation thérapeutique
/
Carcinome hépatocellulaire
/
Imagerie par résonance magnétique de diffusion
/
Diagnostic
/
Tumeurs du foie
/
Méthodes
/
Récidive tumorale locale
Type d'étude:
Etude diagnostique
Limites du sujet:
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Journal of Zhejiang University. Medical sciences
Année:
2014
Type:
Article
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