Influence of Cibotium barametz and its processed samples on haemorheology index in mice with adjuvant arthritis / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 2170-2173, 2008.
Article
Dans Chinois
| WPRIM
| ID: wpr-252173
ABSTRACT
<p><b>OBJECTIVE</b>To discuss the influence of the rhizome of Cibotium barametz on the heamorheology index in mice with adjuvant arthritis and to compare the effect of raw medicinals with that of the processed ones.</p><p><b>METHOD</b>Mice was injected with Freund's complete adjuvant on the rihgt behind foot to make model of adjuvant arthritis (AA). Hydroxyacrbamide tablets were orally administrated by mice with AA to make model of AA due to deficiency in the kidney (DK-AA). And then we determined the heamorheology index of the normal group, positive control group, AA group, DK-AA group and medicinals-treated groups.</p><p><b>RESULT</b>In the groups of AA, and DK-AA, the heamorheology index, such as high shearing, middle shearing, low shearing, plasma viscosity, whole blood reduction viscosity, erythrocyte aggregation exponent, erythrocyte degeneration exponent, sedimentation, sedimentation equation K value, erythrocyte rigidity exponent, erythrocyte electrophoresis time, casson viscosity, casson yield stress, increased significantly. After treated with Cibotium barametz, the heamorheology index except red blood count, packed cell volume, fibrinogen decreased obviously to get normal.</p><p><b>CONCLUSION</b>Rhizome of Cibotium barametz could promote heamorheology in mice with AA and DK-AA to exhibit effect of promoting blood circulation and remove blood stasis. The medicinal rhizomes processed with sand have the effect enhanced.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Arthrite expérimentale
/
Médicaments issus de plantes chinoises
/
Répartition aléatoire
/
Chimie
/
Adjuvant Freund
/
Hémorhéologie
/
Fougères
/
Utilisations thérapeutiques
/
Modèles animaux de maladie humaine
/
Traitement médicamenteux
Type d'étude:
Essai clinique contrôlé
Limites du sujet:
Animaux
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
China Journal of Chinese Materia Medica
Année:
2008
Type:
Article
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