Whole-genome sequencing: a new approach for understanding of pathogenesis and individualized treatment of cancer / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 103-108, 2013.
Article
Dans Chinois
| WPRIM
| ID: wpr-252657
ABSTRACT
With the development of sequencing technology, the cost of whole-genome sequencing was significantly declined.Meanwhile, with the application of combined whole-genome sequencing with epigenetic analysis on methylation and histone acetylation, the comprehensive and systematic analysis of numerous samples became a reality and we are able to re-understand the genesis and development of cancer. New ideas are emerging in comparative genomics research methods, from comparison of genomes among different individuals to horizontal self-comparison of different tissues and vertical self-comparison of genomes recently.Individualized diagnosis and treatment of cancer has shown a bright future.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Thérapeutique
/
Génome humain
/
Analyse de séquence d'ADN
/
Médecine de précision
/
Génétique
/
Méthodes
/
Tumeurs
Type d'étude:
Etude d'étiologie
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Journal of Zhejiang University. Medical sciences
Année:
2013
Type:
Article
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