Clinical efficacy of Yangjing Decoction on idiopathic asthenozoospermia / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the clinical effect of the Chinese medicine Yangjing Decoction on idiopathic asthenospermia.</p><p><b>METHODS</b>This study included 62 patients with idiopathic asthenospermia diagnosed with the computer-assisted semen analysis system and other methods based on the WHO guidelines. The patients were equally randomized to a trial and a control group, the former treated with Yangjing Decoction at the dose of 400 ml bid, and the latter with Yougui Capsules tid, both for a course of 6 months. Then we analyzed the changes in sperm concentration and percentage of grade a + b sperm in the patients, as well as the pregnancy in their wives.</p><p><b>RESULTS</b>Compared with the controls, the patients of the trial group showed a significantly elevated percentage of grade a + b sperm after 6 months medication (P < 0.01), though no statistically significant differences were observed in sperm concentration (P > 0.05). The total rate of effectiveness was 87.09% and 7 pregnancies were achieved in the trial group, as compared with 66.74% and 3 pregnancies in the controls (P < 0.05).</p><p><b>CONCLUSION</b>Yangjing Decoction can significantly improve sperm vitality, and has a desirable effect on idiopathic asthenospermia.</p>