The changes and their clinical significance of D-dimer and platelet glycoprotein in patients with coronary heart disease / 中华心血管病杂志
Chinese Journal of Cardiology
;
(12): 724-726, 2005.
Article
Dans Chinois
| WPRIM
| ID: wpr-253076
ABSTRACT
<p><b>OBJECTIVE</b>To explore the changes and their clinical significance of D-dimer and platelet glycoprotein (GP) in patients with coronary heart disease.</p><p><b>METHODS</b>D-dimer and GP in 20 patients with stable angina (SA group), 48 patients with unstable angina (UA group), and 20 control cases were measured. The changes of D-dimer and GP in patients with and without coronary events were compared. The sensitivity of those changes in the diagnosis of coronary events was evaluated.</p><p><b>RESULTS</b>There were significant differences of D-dimer and GP between UA group and SA group or control group (P < 0.01), while there was no significant difference between SA group and control group (P > 0.05). There were also significant differences of D-dimer and GP between patients with coronary events and patients without coronary events (P < 0.05). In the sensitivity test for detecting coronary events, D-dimer and GPIIb, GPIIIa were much more sensitive than other parameters.</p><p><b>CONCLUSIONS</b>D-dimer and GPIIb, GPIIIa may be regarded as the indexes of coronary thrombosis and used for predicting the severity of coronary events.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Produits de dégradation de la fibrine et du fibrinogène
/
Glycoprotéines de membrane plaquettaire
/
Études cas-témoins
/
Complexe glycoprotéique IIb-IIIa de la membrane plaquettaire
/
Maladie coronarienne
/
Glycoprotéine-IIb de membrane plaquettaire
/
Diagnostic
/
Angor instable
/
Métabolisme
/
Infarctus du myocarde
Type d'étude:
Etude diagnostique
/
Étude observationnelle
/
Facteurs de risque
Limites du sujet:
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Chinese Journal of Cardiology
Année:
2005
Type:
Article
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