Genotypes of hepatitis B virus in Henan Luohe area / 中华实验和临床病毒学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To determine the main genotype of hepatitis B virus (HBV) prevailed in Henan Luohe area.</p><p><b>METHODS</b>Serum specimens were collected from 94 HBsAg positive individuals, and HBV S gene were obtained by PCR amplifying, and the gene sequences were analyzed and the polygenetic tree was drawn by the software MEGA3.</p><p><b>RESULTS</b>About 75.7% samples of HBV S gene clustered in genotype C, about 20% samples clustered at genotype B in the HBV polygenetic tree, about 4.3% samples clustered at genotype D in the HBV polygenetic tree.</p><p><b>CONCLUSION</b>The main genotype of hepatitis B virus prevalent in Henan Luohe is genotype C, genotype B is rarely seen, and genotype D is rarely seen.</p>