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Detection of human papillomavirus in tissues of esophageal carcinomas by polymerase chain reaction / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology ; (6): 251-253, 2008.
Article Dans Chinois | WPRIM | ID: wpr-254091
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the relationship between the human papillomavirus (HPV) and esophageal carcinomas.</p><p><b>METHODS</b>We detected HPV DNA in 31 fresh tissue of esophageal carcinomas from Linzhou City, Henan Province, by PCR with the general primer set of GP5+/6+ for HPV L1 gene and type-specific primer sets for HPV16 and 18 as well.</p><p><b>RESULTS</b>29 from 31 esophageal carcinoma samples were HPV positive and the rate was 93.5%. Among the samples detected, 19 were HPV16E6 positive and rate was 61.3%, eight were HPV18 E6 positive and rate was 25.8%; our result also showed five were the multiple infection containing HPV16 and 18 as well and the rate was 71.0%.</p><p><b>CONCLUSION</b>The high rate of HPV in the esophageal carcinoma samples suggested that HPV plays an etiologic role in the development of esophageal cancer in Linzhou City, Henan Province.</p>
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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Virologie / Tumeurs de l&apos;oesophage / Carcinomes / Chine / Protéines des oncogènes viraux / Réaction de polymérisation en chaîne / Amorces ADN / Protéines de capside / Papillomavirus humain de type 16 / Papillomavirus humain de type 18 Type d'étude: Etude diagnostique Limites du sujet: Adulte / Adulte très âgé / Femelle / Humains / Mâle Pays comme sujet: Asie langue: Chinois Texte intégral: Chinese Journal of Experimental and Clinical Virology Année: 2008 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Virologie / Tumeurs de l&apos;oesophage / Carcinomes / Chine / Protéines des oncogènes viraux / Réaction de polymérisation en chaîne / Amorces ADN / Protéines de capside / Papillomavirus humain de type 16 / Papillomavirus humain de type 18 Type d'étude: Etude diagnostique Limites du sujet: Adulte / Adulte très âgé / Femelle / Humains / Mâle Pays comme sujet: Asie langue: Chinois Texte intégral: Chinese Journal of Experimental and Clinical Virology Année: 2008 Type: Article