Specific T-cell responses to Mycobacterium tuberculosis protein ESAT-6 in Chinese HIV positive individuals / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 124-126, 2008.
Article
Dans Chinois
| WPRIM
| ID: wpr-254123
ABSTRACT
<p><b>OBJECTIVE</b>To detect TB specific T cell responses by using the recombinant ESAT-6 protein as stimulus in Chinese HIV infected patients.</p><p><b>METHODS</b>ELISPOT-IFN-gamma assay by using the recombinant ESAT-6 protein as stimulus to detect specific T cell responses in HIV+ patients with or without clinical manifestation of TB diseases.</p><p><b>RESULTS</b>Recombinant ESAT-6 protein specific T cell responses show significant high frequencies in both of TB patients with or without HIV infection than that in the healthy control and HIV+ group without clinical TB diseases.</p><p><b>CONCLUSION</b>The ELISPOT-IFN-gamma assay by using recombinant ESAT-6 protein as stimulus could be used in diagnoses of TB infection in Chinese HIV infected patients.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Protéines bactériennes
/
Tuberculose
/
Sang
/
Protéines recombinantes
/
Agranulocytes
/
Lymphocytes T
/
Infections à VIH
/
Techniques immunoenzymatiques
/
Interféron gamma
/
Biologie cellulaire
Limites du sujet:
Adulte
/
Adulte très âgé
/
Aged80
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Chinese Journal of Experimental and Clinical Virology
Année:
2008
Type:
Article
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