Epidemiology, diagnosis and treatment of Middle East respiratory syndrome / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 443-450, 2015.
Article
Dans Chinois
| WPRIM
| ID: wpr-255171
ABSTRACT
Middle East respiratory syndrome (MERS) has raised global public health concerns. The recent outbreak of MERS coronavirus (MERS-CoV) infection has led to 1 338 laboratory-confirmed cases in 26 countries worldwide as reported till 19 June, 2015. MERS-CoV may be considered a zoonotic virus that has crossed the species barrier to humans, but the pathogenesis and the routes of transmission are not completely understood. Most MERS-CoV cases reported thus far have a history of residence in or travel to the Middle East. Human-to-human transmission though was observed on some occasions in Korea, it is documented as non-sustainable event. The envelope spike glycoprotein on the surface of MERS-CoV which mediates receptor binding, membrane fusion and viral entry is thought to be involved in the mechanism of MERS-CoV.No specific and effective treatment for MERS-CoV is currently recommended, although supportive treatment has played an important role. Prophylactic strategies are necessary to prevent MERS-CoV infection.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Physiologie
/
Thérapeutique
/
Virulence
/
Épidémiologie
/
Infections à coronavirus
/
Diagnostic
/
Pénétration virale
/
Glycoprotéine de spicule des coronavirus
/
Coronavirus du syndrome respiratoire du Moyen-Orient
/
Métabolisme
Type d'étude:
Etude diagnostique
/
Étude de dépistage
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Journal of Zhejiang University. Medical sciences
Année:
2015
Type:
Article
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