Effect of spinal manipulation on brain functional activity in patients with lumbar disc herniation / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 124-137, 2015.
Article
Dans Chinois
| WPRIM
| ID: wpr-255222
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effects of spinal manipulation (SM) on brain functional activity in patients with lumbar disc herniation (LDH).</p><p><b>METHODS</b>Eleven patients with LDH were recruited in the study. All patients received 6 times of lumbar SM treatment and then clinical efficacy was evaluated. All patients received brain functional magnetic resonance imaging (fMRI) scans before and after SM treatment.</p><p><b>RESULTS</b>Three subjects dropped out and 8 subjects completed the study, among whom 4 cases were effective and 4 ineffective after SM treatment. The required pressure value producing the same level (VAS 50) pain was (7.43 ± 1.47) kg and (10.53 ± 0.55) kg before and after SM treatment in effective patients(P<0.05); however, there was no significant difference in ineffective patients (P>0.05). Compared to pre-treatment level, the brain functional activity in effective patients was mainly inhibited, the inhibited areas were located in the right side of prefrontal cortex and cerebellum; while the brain functional activity was generally enhanced in ineffective patients.</p><p><b>CONCLUSION</b>SM can affect the brain functional activity of patients with LDH, the inhibited areas is mainly located in prefrontal cortex and cerebellum when SM treatment is effective.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Thérapeutique
/
Encéphale
/
Imagerie par résonance magnétique
/
Manipulation vertébrale
/
Déplacement de disque intervertébral
/
Vertèbres lombales
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Journal of Zhejiang University. Medical sciences
Année:
2015
Type:
Article
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