Sodium transport and its regulation of acutely isolated alveolar type II cells / 南方医科大学学报
Journal of Southern Medical University
;
(12): 476-478, 2006.
Article
Dans Chinois
| WPRIM
| ID: wpr-255280
ABSTRACT
<p><b>OBJECTIVE</b>To observe the sodium current of acutely isolated alveolar type II cells and its regulation.</p><p><b>METHODS</b>After isolation the AT II cells, the whole cell sodium current were recorded in 5 hours with patch-clamp in whole-cell mode, and the effect of amiloride and terbutaline on the current was investigated.</p><p><b>RESULTS</b>The amiloride-sensitive current of AT II cells were recorded, which could be obviously stimulated by terbutaline.</p><p><b>CONCLUSION</b>Acutely isolated AT II cells can be valuable for studying electrophysiological characteristics of sodium channels even under pathological conditions.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pharmacologie
/
Physiologie
/
Alvéoles pulmonaires
/
Sodium
/
Terbutaline
/
Transport biologique
/
Canaux sodiques
/
Séparation cellulaire
/
Rat Sprague-Dawley
/
Techniques de patch-clamp
Limites du sujet:
Animaux
langue:
Chinois
Texte intégral:
Journal of Southern Medical University
Année:
2006
Type:
Article
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