The investigation of tracheas transplantation by wrapping in a muscle flap / 中华整形外科杂志
Chinese Journal of Plastic Surgery
;
(6): 214-216, 2003.
Article
Dans Chinois
| WPRIM
| ID: wpr-256443
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the possibility of tracheas transplantation by wrapping it in a muscle flap.</p><p><b>METHODS</b>With a dog model, a number of tracheas were separately wrapped in the unilateral sternocephalic muscle flap and the bilateral sternohyoid-sternothyroid muscle flap, and placed in the original site. The tracheas autografting was used as a control. The viability was evaluated by the examination of fiberoptic bronchoscopy, histopathology and microangiography, the measurement of tracheal mucosal blood flow and the calculation of survival rate and percentage of patency.</p><p><b>RESULTS</b>The submucosal blood flow of the transplanted tracheas was detected in the unilateral sternocephalic muscle flap group and the bilateral sternohyoid-sternothyroid muscle flap group 1 week after the surgery and gradually reached the level close to the normal in 4 weeks, while the vascular ingrowth was also shown from the wrapped muscle flap into the transplanted tracheas by using a microangiography technique. The histopathological examination demonstrated that the structure of the transplanted tracheas was quite same as the original one and its inner surface was also covered with pseudostratified columnar ciliary epithelia. However, in the control group, the mucous membranes turned black one week after the transplantation and all dogs died from the graft necrosis.</p><p><b>CONCLUSION</b>The tracheas wrapped in a muscular flap could survive well for a long time.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Physiologie
/
Débit sanguin régional
/
Lambeaux chirurgicaux
/
Facteurs temps
/
Trachée
/
Transplantation
/
Transplantation autologue
/
Mortalité
/
Épithélium
Type d'étude:
Étude pronostique
Limites du sujet:
Animaux
langue:
Chinois
Texte intégral:
Chinese Journal of Plastic Surgery
Année:
2003
Type:
Article
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