Application of TRUST, TP-ELISA and TPPA in the serologic diagnosis of syphilis / 中华男科学杂志
National Journal of Andrology
; (12): 1020-1022, 2012.
Article
Dans Zh
| WPRIM
| ID: wpr-256998
Responsable en Bibliothèque :
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the application value of toluidine red unheated serum test (TRUST), treponema pallidum enzyme-linked immunosorbent assay (TP-ELISA) and treponema pallidum particle agglutination assay (TPPA) in the serologic diagnosis of syphilis.</p><p><b>METHODS</b>We collected serum samples from 12 622 inpatients, 2 253 outpatients and 1 500 subjects in the medical examination center, and screened them by TRUST and TP-ELISA, followed by quantitative tests using TRUST and TPPA.</p><p><b>RESULTS</b>Among the 16 375 cases, clinically diagnosed syphilis was confirmed in 384, with a positive rate of 100% either by TRUST (1:2 -1 :16) or TPPA (1:80 - 1:2 560), and 92.2% by TP-ELISA.</p><p><b>CONCLUSION</b>TP-ELISA and TRUST should be simultaneously used for syphilis screening, but not TP-ELISA alone, and the results should be confirmed by TPPA. The combination of the three methods plays a valuable role in reducing the misdiagnosis and missed diagnosis, and contributes to the early and accurate diagnosis of syphilis.</p>
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Treponema pallidum
/
Sang
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Test ELISA
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Sérodiagnostic de la syphilis
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Syphilis
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Diagnostic
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Méthodes
Type d'étude:
Diagnostic_studies
Limites du sujet:
Adolescent
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Adult
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Aged
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Aged80
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Child
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Child, preschool
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Humans
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Infant
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Newborn
langue:
Zh
Texte intégral:
National Journal of Andrology
Année:
2012
Type:
Article