Research advances in the application of methylprednisolone in the treatment of acute spinal cord injury / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 680-685, 2014.
Article
Dans Anglais
| WPRIM
| ID: wpr-257694
ABSTRACT
Acute spinal cord injury(ASCI),mainly caused by traffic accidents and fall injuries,is a catastrophic event that can profoundly affect the trajectory of a patient's life. Debate continues over the medical management of ASCI,in particular the usefulness,dosage,and potential risks of methylprednisolone(MP). Although the results of American National Acute Spinal Cord Injury Study 2 and 3 trials led to the wide adoption of a high-dose MP regimen for ASCI patients,the reliabilities of their study methods and data were still questionable. Based on the currently available literature,we conclude that high-dose MP is no longer a recommended therapy for ASCI;however,due to the lack of effective treatment,it remains a useful option for this condition.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Traumatismes de la moelle épinière
/
Méthylprednisolone
/
Essais cliniques comme sujet
/
Résultat thérapeutique
/
Neuroprotecteurs
/
Utilisations thérapeutiques
/
Traitement médicamenteux
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Acta Academiae Medicinae Sinicae
Année:
2014
Type:
Article
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