Relation between Beta-2-glycoprotein I and hepatitis B virus surface antigen / 中华肝脏病杂志

ABSTRACT

<p><b>OBJECTIVE</b>To clarify the binding character between Beta-2-glycoprotein I (Beta-2-GPI) and HBsAg.</p><p><b>METHODS</b>Beta-2-GPI was purified from human plasma and labelled with biotin. Solid phase enzyme linked absorbance assay was used to investigate its binding with HBsAg.</p><p><b>RESULTS</b>Biotinylated Beta-2-GPI was found to bind HBsAg and the reaction could be inhibited by excess unlabelled Beta-2-GPI.</p><p><b>CONCLUSIONS</b>Beta-2-GPI may play a role in hepatitis B virus infection.</p>