Relationship of polymorphism of SG13S114A/T in ALOX5AP gene with atherosclerotic cerebral infarction / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 630-633, 2009.
Article
Dans Chinois
| WPRIM
| ID: wpr-259255
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the relationship of the polymorphism of SG13S114A/T in ALOX5AP gene with atherosclerotic cerebral infarction (ACI).</p><p><b>METHODS</b>By polymerase chain reaction and restriction fragment length polymorphism, polymorphism of SG13S114A/T in ALOX5AP gene in 412 cases with ACI and 368 non-ACI controls were analyzed.</p><p><b>RESULT</b>There were no statistically significant differences in the ALOX5AP gene SG13S114 AA genotype and A allele frequencies between ACI group and control group (P>0.05).</p><p><b>CONCLUSION</b>The results do not support genotype SG13S114 A allele as the risk gene for ACI.control group.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Polymorphisme de restriction
/
Artériosclérose intracrânienne
/
Infarctus cérébral
/
Allèles
/
Protéines d'activation de la 5-lipoxygénase
/
Génétique
/
Génotype
Limites du sujet:
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Journal of Zhejiang University. Medical sciences
Année:
2009
Type:
Article
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