Prognostic value of lymph node ratio and N stage in stage III colorectal cancer / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 553-557, 2015.
Article
Dans Chinois
| WPRIM
| ID: wpr-260313
ABSTRACT
<p><b>OBJECTIVE</b>To compare the prognostic value of lymph node ratio and N staging in stage III colorectal cancer.</p><p><b>METHODS</b>The clinicopathologic factors and follow-up data of 304 cases with stage III colorectal cancer from January 1998 to December 2011 were analyzed retrospectively. Multivariate analysis was performed using Cox proportional hazard regression model in forward stepwise regression. Patients were divided into different subgroups according to the number of lymph nodes sample.</p><p><b>RESULTS</b>LNR and N stage were independent risk factors for stage III colorectal cancer, the prognostic value of LNR was better than that of N stage [Odds ratio were 1.838(95% CI1.563~2.161) vs. 1.625 (95% CI1.392~1.898)]. Subgroup analysis showed that, when the number of lymph nodes sample was less than 13, the prognostic value of LNR was better than that of N stage (Odds ratio were 1.836 vs. 1.639). But when the number of lymph nodes sample was more than 13, they were comparable (Odds ratio were 1.876 vs. 1.853).</p><p><b>CONCLUSIONS</b>The prognostic value of LNR and N stage were comparable for stage III colorectal cancer, but when the number of lymph nodes sample was less than 13, LNR was more valuable.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pronostic
/
Tumeurs colorectales
/
Modèles des risques proportionnels
/
Analyse multifactorielle
/
Études rétrospectives
/
Noeuds lymphatiques
/
Métastase lymphatique
/
Stadification tumorale
Type d'étude:
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Chinese Journal of Gastrointestinal Surgery
Année:
2015
Type:
Article
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