A case of hyperinsulinemic obese female adolescent with virilization
Journal of the Korean Academy of Family Medicine
;
: 1419-1427, 1998.
Article
Dans Coréen
| WPRIM
| ID: wpr-26266
ABSTRACT
BACKGROUND:
Being obese during adolescence leads to undue physical or psychological problems and may increase the incidence of cardiovascular disease or endocrinological disorders. Recently authors have experienced a case of hyperinsulinemic obese girl with virilization. We report it with a review of the literature. CASE A 17-year old female came into 'obesity clinic' of Asan Medical Center due to weight gain. She had virilizing feature, hirsutism, underdeveloped female sexual characteristics, and acanthosis nigricans. Work-up by laboratory tests and imaging studies showed very severe obesity with metabolic disturbances, and hyperandrogenism with hyperinsulinemia. Treatment for obesity was multidisciplinary method including behavior modification, calorie restriction, exercise, and medication with fluoxetine 40mg po qd, and for hyperandrogenism, provera 10mg po qd was described.CONCLUSIONS:
Severe hyperinsulinemia in obese female leads to male-type hirsutism, disturbance of menstrual cycle, abdominal obesity, and cardiovascular disorders. One of the physical findings of hyperinsulinemia or insulin resistance is acanthosis nigricans. So, if an female obese patient have acanthosis nigricans with hyperinsulinemia, should be assessed and treated for risk factors of cardiovascular disorders and hormonal disturbances.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Virilisme
/
Thérapie comportementale
/
Obésité morbide
/
Insulinorésistance
/
Maladies cardiovasculaires
/
Prise de poids
/
Fluoxétine
/
Incidence
/
Facteurs de risque
/
Acétate de médroxyprogestérone
Type d'étude:
Etude d'étiologie
/
Etude d'incidence
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adolescent
/
Femelle
/
Humains
langue:
Coréen
Texte intégral:
Journal of the Korean Academy of Family Medicine
Année:
1998
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS