Determination of ADAMTS13 antigen and activity levels in patients with acute myocardial infarction and acute ischemic stroke / 中华血液学杂志
Chinese Journal of Hematology
;
(12): 161-163, 2008.
Article
Dans Chinois
| WPRIM
| ID: wpr-262914
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the ADAMTS13 antigen levels and activity in patients with acute myocardial infarction (AMI) and acute ischemic stroke (AIS), and explore its significance in these diseases.</p><p><b>METHODS</b>ADAMTS13 activity levels were detected by a new developed Frests-vWF73 kit, ADAMTS13 antigen levels by ELISA kit, and vWF multimers by electrophoresis.</p><p><b>RESULTS</b>ADAMTS13 antigen in normal control, AMI and AIS was (878 +/- 198), (618 +/- 188) and (702 +/- 155) U/L, and ADAMTS13 activity was (81.7 +/- 13.9)%, (59.2 +/- 22.1 )% and (65.4 +/- 15.8)%, respectively, being significantly decreased in AMI and AIS patients.</p><p><b>CONCLUSION</b>ADMATS13 might involve in arterial infarction diseases.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Sang
/
Facteur de von Willebrand
/
Infarctus encéphalique
/
Protéines ADAM
/
Protéine ADAMTS13
/
Métabolisme
/
Infarctus du myocarde
Limites du sujet:
Adulte très âgé
/
Aged80
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Chinese Journal of Hematology
Année:
2008
Type:
Article
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