A pilot study of repair of periodontal bone defects with carbonated phosphate bone cement modified with synthesized peptides in dogs / 中华口腔医学杂志
Chinese Journal of Stomatology
;
(12): 464-466, 2003.
Article
Dans Chinois
| WPRIM
| ID: wpr-263481
ABSTRACT
<p><b>OBJECTIVE</b>To explore the possibility of repairing periodontal defects with carbonated calcium phosphate bone cement (CCPBC) modified with synthesized peptides.</p><p><b>METHODS</b>Periodontal bone defects in 4 dogs were surgically created and then restored directly with hydroxyapatite (HA), Perioglass, CCPBC and CCPBC modified with peptides. The results were compared at different levels.</p><p><b>RESULTS</b>Bone replacement materials were lost in HA and Perioglass groups. In the HA group defects were restored with connective tissue. Perioglass group had only a little new bone around materials by alveolar bone. CCPBC could firmly stay in bone defects to maintain the space of bone defects even without membrane use. CCPBC modified with peptides was superior to HA, Perioglass, and CCPBC, surrounded by a great deal of new bone.</p><p><b>CONCLUSION</b>Under limitation of this study, CCPBC modified with peptides has some osteoinuctive activity and may have good prospect for the clinical application in periodontal defect repair.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Thérapeutique
/
Ciments osseux
/
Régénération osseuse
/
Phosphates de calcium
/
Résorption alvéolaire
/
Durapatite
/
Substituts osseux
Limites du sujet:
Animaux
langue:
Chinois
Texte intégral:
Chinese Journal of Stomatology
Année:
2003
Type:
Article
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