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Changing Grains for the Prevention and Treatment of Kashin-Beck Disease in Children: a Meta-analysis / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences ; (12): 308-311, 2015.
Article Dans Anglais | WPRIM | ID: wpr-264583
ABSTRACT
To evaluate the efficacy of changing grains on the prevention and treatment of Kashin-Beck Disease (KBD) in children, community-based trials were acquired from seven electronic databases (up to July 2014). As a result, the methodological quality of the six trials that have been included into our analysis was low. The pooled ORs favoring the prevention and treatment effects of changing grains were 0.15 (95% CI 0.03-0.70) and 2.13 (95% CI 1.44-3.16) respectively by meta-analysis. Subgroup analysis demonstrated the pooled OR favoring treatment effect of exchanging grains rather than drying grains both compared with endemic grains. The results showed that changing grains had obvious effects on the prevention and treatment of KBD in children. However, the evidences were limited by the potential biases and confounders. Large and well-designed trials are still needed.
Sujets)
Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Physiologie / Thérapeutique / Grains comestibles / Recherche participative basée sur la communauté / Maladie de Kashin-Beck Type d'étude: Revues systématiques évaluées Limites du sujet: Adolescent / Enfant / Enfant d'âge préscolaire / Humains / Bébé / Nouveau-né langue: Anglais Texte intégral: Biomedical and Environmental Sciences Année: 2015 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Physiologie / Thérapeutique / Grains comestibles / Recherche participative basée sur la communauté / Maladie de Kashin-Beck Type d'étude: Revues systématiques évaluées Limites du sujet: Adolescent / Enfant / Enfant d'âge préscolaire / Humains / Bébé / Nouveau-né langue: Anglais Texte intégral: Biomedical and Environmental Sciences Année: 2015 Type: Article