Mechanism and early evaluation of CNS infiltration in acute lymphocytic leukemia-review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1361-1364, 2013.
Article
Dans Chinois
| WPRIM
| ID: wpr-265013
ABSTRACT
Central nervous system (CNS) is one of places in which direct infiltration and involvement or relapse occur in adult lymphocytic leukemia. The main mechanism of CNS infiltration in leukemia is associated with blood brain barrier (BBB), however the ALL CNS infiltration is difficulty early predicted and evaluated.For this reason, the studies on accurately evaluating the ALL CNS infiltration have important significance for early diagnosis and adjustment of therapeutic regimen, performance of individualised treatment and improvement of ALL patient's prognosis. In this article, the pathway of ALL CNS infiltration and its molecular mechanism, the evaluation methods for BBB function are reviewed.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Barrière hémato-encéphalique
/
Tumeurs du système nerveux central
/
Diagnostic précoce
/
Diagnostic
/
Leucémie-lymphome lymphoblastique à précurseurs B et T
/
Invasion tumorale
Type d'étude:
Etude diagnostique
/
Étude de dépistage
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Journal of Experimental Hematology
Année:
2013
Type:
Article
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