Regulatory T Cells in Hepatitis B and C Virus Infections
Immune Network
;
: 330-336, 2016.
Article
Dans Anglais
| WPRIM
| ID: wpr-26675
ABSTRACT
Hepatitis B virus (HBV) and hepatitis C virus (HCV) are hepatotropic viruses that establish chronic persistent infection by effectively escaping the host immune response and can cause immune-mediated liver injury. It has recently become apparent that regulatory T (Treg) cells, specifically CD4⁺CD25⁺Foxp3⁺ Treg cells, modulate viral diseases by suppressing antiviral immune responses and regulating inflammatory host injury. The roles of Treg cells in HBV and HCV infections range from suppressing antiviral T cell responses to protecting the liver from immune-mediated damage. This review describes Treg cells and subpopulations and focuses on the roles of these cells in HBV and HCV infections.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Nations Unies
/
Maladies virales
/
Virus de l'hépatite B
/
Lymphocytes T régulateurs
/
Hepacivirus
/
Hépatite
/
Hépatite B
/
Foie
langue:
Anglais
Texte intégral:
Immune Network
Année:
2016
Type:
Article
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