Epstein-Barr Virus Associated Hemophagocytic Syndrome after Scrub Typhus Infection / 감염과화학요법
Infection and Chemotherapy
; : 330-333, 2016.
Article
de En
| WPRIM
| ID: wpr-26684
Bibliothèque responsable:
WPRO
ABSTRACT
There have been a small number of cases of scrub typhus-associated hemophagocytic syndrome (HPS), most of which were treated successfully using adequate antibiotics. Here, we report a case of Epstein-Barr virus (EBV)-associated HPS after scrub typhus infection that was not improved using antirickettsial treatment. A 73-year-old male who had been diagnosed with scrub typhus according to an eschar and a positive serology was transferred to our institution because of a persistent fever despite 7-day doxycycline therapy. Physical and laboratory data showed hepatosplenomegaly, bicytopenia, hyperferritinemia, and hypofibrinogenemia. A bone marrow examination (BM) revealed hypercellular marrow with hemophagocytosis and histiocyte infiltration. EBV was detected in BM aspirates using polymerase chain reaction. After a diagnosis of HPS was made, the patient was treated successfully using high-dose steroids.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Stéroïdes
/
Moelle osseuse
/
Myélogramme
/
Fièvre fluviale du Japon
/
Réaction de polymérisation en chaîne
/
Doxycycline
/
Herpèsvirus humain de type 4
/
Infections à virus Epstein-Barr
/
Diagnostic
/
Lymphohistiocytose hémophagocytaire
Type d'étude:
Diagnostic_studies
Limites du sujet:
Aged
/
Humans
/
Male
langue:
En
Texte intégral:
Infection and Chemotherapy
Année:
2016
Type:
Article