Polymorphism of LW blood group gene in Chinese population / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 691-693, 2008.
Article
Dans Chinois
| WPRIM
| ID: wpr-267909
ABSTRACT
In order to study the polymorphism of Landsteiner-Wiener (LW) blood group gene in Chinese population, peripheral blood samples anticoagulated with EDTA from 160 unrelated volunteer blood donors were randomly collected, and genomic DNA were extracted. 160 DNA samples were analyzed for exon 1 of LW gene by direct DNA sequencing, and detected for LWa/LWb allele by improved PCR-SSP genotyping. The results showed that all LW allele in 160 donors were LWa homozygous, and the LWa allele occurred commonly. In conclusion, LWa allele occurs with incidence of 100% of donors in this study, while LWb allele has not been found in Chinese population.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Polymorphisme génétique
/
Donneurs de sang
/
Antigènes de groupe sanguin
/
Molécules d'adhérence cellulaire
/
Exons
/
Analyse de séquence d'ADN
/
Asiatiques
/
Allèles
/
Génétique
/
Homozygote
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Journal of Experimental Hematology
Année:
2008
Type:
Article
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