Impact of chronic prostatitis/chronic pelvic pain syndrome on sperm DNA fragmentation and nucleoprotein transition / 中华男科学杂志
National Journal of Andrology
; (12): 907-911, 2013.
Article
de Zh
| WPRIM
| ID: wpr-268033
Bibliothèque responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the impact of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) on sperm DNA fragmentation and nucleoprotein transition.</p><p><b>METHODS</b>Based on the recommended methods in the WHO Laboratory Manual for the Examination and Processing of Human Semen (5th ed), we conducted routine semen analysis for 65 CP/CPPS patients and 30 healthy men. We also analyzed the results of papanicolaou staining, sperm DNA fragmentation and sperm nucleoprotein transition.</p><p><b>RESULTS</b>Compared with the healthy control males, the CP/CPPS patients showed significant decreases in sperm concentration ([134.05 +/- 99.80] vs [94.75 +/- 92.07]) x 10(6)/ml, P <0.05), the percentage of morphologically normal sperm ([7.26 +/- 2.28] vs [5.61 +/- 3.40]%, P <0.05) and sperm progressive motility ([59.18 +/- 16.06] vs [47.68 +/- 17.62]%, P<0.05), but dramatic increases in sperm DNA fragmentation ([22.92 +/- 11.51] vs [43.58 +/- 17.07%, P<0.01) and sperm nucleoprotein transition ([23.26 +/- 5.97] vs [32.14 +/- 8.79]%, P<0.01).</p><p><b>CONCLUSION</b>CP/CPPS significantly reduces sperm quality and male fertility.</p>
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Prostatite
/
Numération des spermatozoïdes
/
Mobilité des spermatozoïdes
/
Études cas-témoins
/
Fragmentation de l'ADN
/
Analyse du sperme
/
Génétique
/
Nucléoprotéines
Type d'étude:
Observational_studies
Limites du sujet:
Adult
/
Humans
/
Male
langue:
Zh
Texte intégral:
National Journal of Andrology
Année:
2013
Type:
Article