Biology of thioredoxin and its association with Alzheimer's disease and Parkinson's disease / 药学学报
Acta Pharmaceutica Sinica
;
(12): 1-8, 2008.
Article
Dans Chinois
| WPRIM
| ID: wpr-268181
ABSTRACT
Thioredoxin (Trx) is a crucial protein for antioxidative defense, as well as a redox regulator of the intra- and extracellular signaling pathways and transcription factors. In this review, we focus on mammalian Trx and its association with Alzheimer's disease (AD) and Parkinson's disease (PD). Based on the evidence of neuroprotective effects of Trx, up-regulation of Trx may be a good strategy for prevention and treatment of AD and PD.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Oxydoréduction
/
Maladie de Parkinson
/
Physiologie
/
Thiorédoxines
/
Apoptose
/
Neuroprotecteurs
/
Maladie d'Alzheimer
/
Métabolisme
/
Antioxydants
Limites du sujet:
Animaux
/
Humains
langue:
Chinois
Texte intégral:
Acta Pharmaceutica Sinica
Année:
2008
Type:
Article
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