Clinical and pathologic characteristics of primary angiosarcoma of breast / 中华病理学杂志
Chinese Journal of Pathology
;
(12): 598-601, 2006.
Article
Dans Chinois
| WPRIM
| ID: wpr-268889
ABSTRACT
<p><b>OBJECTIVE</b>To study the clinical and pathologic characteristics of primary angiosarcoma of breast.</p><p><b>METHODS</b>Five cases of primary angiosarcoma of breast were reviewed. Immunohistochemical study (SP method) for factor VIII-related antigen, CD31, CD34, estrogen receptor, progesterone receptor and c-erbB-2 was performed. The clinical data were also analyzed.</p><p><b>RESULTS</b>All of the 5 patients had a history of a painless breast lump. Ultrasound examination and mammogram did not reveal any specific findings. Histologically, various degree of cellular pleomorphism was noted. Immunohistochemical study showed a positive expression of endothelial associated antigens of the tumors cells in all the 5 cases. The staining result for estrogen receptor, progesterone receptor and c-erbB-2 was negative.</p><p><b>CONCLUSIONS</b>Primary angiosarcoma of breast is a rare entity. The diagnosis is rather difficult owing to the lack of specific clinical findings and histological heterogeneity. Application of Positive expression of endothelial associated antigens of the tumors cells is helpful in making a pathological diagnosis morphologically.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Chirurgie générale
/
Région mammaire
/
Tumeurs du sein
/
Facteur de von Willebrand
/
Immunohistochimie
/
Études de suivi
/
Tumeur du sein de l'homme
/
Antigènes CD34
/
Antigènes CD31
Type d'étude:
Etude diagnostique
/
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Adulte
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Chinese Journal of Pathology
Année:
2006
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS