Retrospective analysis of 125 cases of pregnancies complicated by rheumatic heart disease / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the impact of rheumatic heart disease on pregnancy.</p><p><b>METHODS</b>A retrospective study was conducted in 125 pregnant women with rheumatic heart disease. These cases were divided into operation (group A) and non-operation (group B), and the cardiac function, pregnancy complications, gestational weeks, delivery modes and outcomes of pregnancy were compared.</p><p><b>RESULTS</b>The cardiac function was significantly improved and pregnancy complications reduced after the cardiac operation with extended gestational weeks, showing significant differences between the two groups (P<0.05). One perinatal fetal death without maternal death occurred in group A, as compared with two maternal and two perinatal deaths in group B. Cesarean section was the primary delivery mode in these cases.</p><p><b>CONCLUSION</b>Surgical interventions can improve the cardiac function, reduce the pregnancy complications and improve the pregnancy outcomes in pregnant women with rheumatic heart disease. Cesarean section is the primary choice for pregnant women with prosthetic heart valve replacement.</p>