X-ray-induced expression changes of TNFSF4 gene in human peripheral blood / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
;
(12): 729-732, 2014.
Article
Dans Anglais
| WPRIM
| ID: wpr-270546
ABSTRACT
This study examined ionizing radiation-induced tumor necrosis factor (ligand) superfamily, member 4 (TNFSF4) mRNA expression changes in human peripheral blood cells and their distribution in a normal population. The results showed that expression level of TNFSF4 mRNA exhibited a dose-dependent response after different irradiation doses, but that was independent of incubation time post-irradiation. Moreover, it was not affected by age and gender in 51 healthy donors. Our studies indicate that TNFSF4 can be considered as a candidate gene to develop a new biodosimeter.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Effets des rayonnements
/
Rayons X
/
Sang
/
Cellules sanguines
/
Marqueurs biologiques
/
Relation dose-effet des rayonnements
/
Ligand de OX40
/
Volontaires sains
Limites du sujet:
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Biomedical and Environmental Sciences
Année:
2014
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS