Allergy-related evidences in relation to serum IgE: data from the China state key laboratory of respiratory disease, 2008-2013 / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
;
(12): 495-505, 2014.
Article
Dans Anglais
| WPRIM
| ID: wpr-270573
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the serum total IgE (tIgE) and specific IgE (sIgE) to common allergens among allergic patients in Guangzhou, China.</p><p><b>METHODS</b>7 085 patients were examined for tIgE and sIgE to 15 allergens, based on the protocols of reversed enzyme allergosorbent test and the sandwich enzyme-linked immunosorbent assay.</p><p><b>RESULTS</b>3 758 (53.04%) patients tested positive for tIgE, and 4 640 (65.49%) for sIgE. Der pteronyssinus, Der farinae, eggs, and cow's milk were the most common allergens leading to higher positive rates of sIgE responses. Several peaks of sensitization were Der pteronyssinus, Der farinae, and Blomia tropicalis at age 10-12; cow's milk at age below 3; eggs at age 4-6. The mean level and positive rate of tIgE tended to increase in subjects sensitized to more allergens. Sensitization to Der pteronyssinus (OR, 1.6; P<0.05), Der farinae (OR, 1.5; P<0.05), Blomia tropicalis (OR, 1.4; P<0.05), Blattella germanica (OR, 1.5; P<0.05), cow's milk (OR, 1.3; P<0.05), and soy beans (OR, 2.0; P<0.05) were independently correlated with allergy-related conditions in preliminary diagnosis.</p><p><b>CONCLUSION</b>The major allergens in Guangzhou include Der pteronyssinus, Der farinae, cow's milk, and eggs. Sensitization to these allergens appears to be predictors of allergy-related disorder.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Maladies de l'appareil respiratoire
/
Sang
/
Immunoglobuline E
/
Allergènes
/
Odds ratio
/
Chine
/
Épidémiologie
/
Études rétrospectives
/
Allergie et immunologie
/
Hypersensibilité
Type d'étude:
Etude d'étiologie
/
Guide de pratique
/
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Adolescent
/
Adulte
/
Adulte très âgé
/
Aged80
/
Enfant
/
Enfant d'âge préscolaire
/
Femelle
/
Humains
/
Bébé
/
Mâle
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Biomedical and Environmental Sciences
Année:
2014
Type:
Article
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