Incidence of seroresistance of syphilis and its relevant factors / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 338-341, 2008.
Article
Dans Chinois
| WPRIM
| ID: wpr-270693
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the incidence of seroresistance of syphilis and analyze its relevant factors.</p><p><b>METHODS</b>The clinical data of 131 patients with syphilis were retrospectively analyzed. The incidence of seroresistance was investigated and the correlation between seroresistance and factors including age, gender, original titer, disease course, and medications were analyzed.</p><p><b>RESULTS</b>The incidence of seroresistance was not significantly different among patients with different ages and genders, but was significantly different among patients with different disease courses, antibody titers, and medications. Patients with a baseline serum rapid plasma reagin (RPR) titer of greater than 1 8, a latent course, or a macrolide therapy history had higher incidences of seroresistance (i. e., 61%, 45.6%, and 72.7% respectively) than those who had a lower RPR titer, a primary course, or a benzathine penicillin therapy history.</p><p><b>CONCLUSION</b>Syphilis patients with a high baseline RPR titer, a latent course, and a macrolides therapy are prone to be seroresistant.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Réagines
/
Sang
/
Sérodiagnostic de la syphilis
/
Syphilis
/
Macrolides
/
Utilisations thérapeutiques
/
Diagnostic
/
Traitement médicamenteux
/
Allergie et immunologie
/
Méthodes
Type d'étude:
Etude diagnostique
/
Etude d'incidence
Limites du sujet:
Adolescent
/
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Acta Academiae Medicinae Sinicae
Année:
2008
Type:
Article
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