The significance of beta-receptor expression in infantile hemangiomas / 中华整形外科杂志
Chinese Journal of Plastic Surgery
;
(6): 290-293, 2013.
Article
Dans Chinois
| WPRIM
| ID: wpr-271204
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the expression and significance of beta-receptor ( p-R) in infantile hemangioma.</p><p><b>METHODS</b>The expression of beta-R was detected by immunohistochemistry in infantile hemangioma (40 cases), venous malformation (20 cases) and normal skin (10 cases).</p><p><b>RESULTS</b>The positive expression rate of beta2-R was 70% (28/40) in infantile hemangioma, while no expression of beta2-R in venous malformation and normal skin. Among 28 cases with positive expression of beta2-R, 24 cases were in proliferative phase. The positive expression of beta2-R in infantile hemangioma was significantly higher than that in venous malformation and normal skin tissue. The positive expression of beta2-R in the proliferative hemangioma and non-proliferative hemangioma was also significantly different (P < 0.05).</p><p><b>CONCLUSIONS</b>beta2-R is specifically expressed in infantile hemangioma, especially in proliferative hemangioma.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Immunohistochimie
/
Études cas-témoins
/
Récepteurs bêta-adrénergiques
/
Hémangiome
/
Métabolisme
Type d'étude:
Étude observationnelle
Limites du sujet:
Femelle
/
Humains
/
Bébé
/
Mâle
langue:
Chinois
Texte intégral:
Chinese Journal of Plastic Surgery
Année:
2013
Type:
Article
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