Women with poor response to ovarian stimulation have increased follicular bone morphogenetic protein-15 levels / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 439-442, 2007.
Article
Dans Chinois
| WPRIM
| ID: wpr-271506
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the levels of bone morphogenetic protein-15 (BMP-15) in human follicular fluid (FF) and its association with response to ovarian stimulation.</p><p><b>METHODS</b>Western blotting was performed to determine the levels of BMP-15 in FF obtained from follicle aspirates in 70 patients undergoing IVF treatment. According to the response to ovarian stimulation the patients were divided into poor responder group and normal responder group.</p><p><b>RESULT</b>BMP-15 levels in FF of poor responders were significantly higher than those in normal responders (1.01 +/- 0.34 vs 0.77 +/- 0.24, P<0.01).</p><p><b>CONCLUSION</b>Increased levels of BMP-15 in FF may be associated with poor response to ovarian stimulation.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Ovaire
/
Induction d'ovulation
/
Liquide folliculaire
/
Technique de Western
/
Hormone de libération des gonadotrophines
/
Protéines et peptides de signalisation intercellulaire
/
Protéine morphogénétique osseuse de type 15
/
Facteur-9 de croissance et de différenciation
/
Hormone folliculostimulante
/
Infertilité féminine
Limites du sujet:
Adulte
/
Femelle
/
Humains
langue:
Chinois
Texte intégral:
Journal of Zhejiang University. Medical sciences
Année:
2007
Type:
Article
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