Relationship between androgen levels and pathological changes of coronary atherosclerosis in elderly males / 浙江大学学报·医学版

ABSTRACT

<p><b>OBJECTIVE</b>To explore the relationship between androgen levels and pathological changes of coronary artery in elderly males.</p><p><b>METHODS</b>One hundred and twenty-eight in-patients who received coronary angiography were divided into four groups single vessel lesion group (SV group), double vessel lesion group (DV group), three vessel lesion group (TV group) and control group. The levels of serum total testosterone (TT) and sex hormone binding globulin (SHBG) were assayed by ELISA, and free testosterone (FT) calculated with the Vermeulen formula.</p><p><b>RESULTS</b>There was significant difference in FT levels among these four groups, while there was no statistical difference in TT levels. FT level in TV group was lower than that in DV group and SV group.</p><p><b>CONCLUSION</b>Serum levels of free testosterone may be correlated with pathological degree of coronary artery.</p>