Study on Serological Blood Group Conversion in BM Empty Phase of ABO-incompatible Allogeneic Stem Cell Transplantation / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 221-224, 2016.
Article
de Zh
| WPRIM
| ID: wpr-272475
Bibliothèque responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To explore the regularity of serological conversion of blood group in BM empty phase of ABO-incompatible allogeneic stem cell transplantation so as to provide the basis for selecting the blood components in blood transfusion.</p><p><b>METHODS</b>Before hematpoietic stem cell transplantation (HSCT), the ABO and RhD blood groups of recipients and donors were identified by salt medium tube method and microcolumn gel method; after transplantation the changes of antigen intensity and antibody titer of ABO blood group in patients were periodically detected.</p><p><b>RESULTS</b>After blood group shift of 33 patients received ABO-incompatible allo-HSCT, the consistent rate of positive and regative types in major ABO incompatible group was 100%; the consistent rate of positive and negative types in minor ABO-incompatible group was 33%, no-consistent rate was 66.7%; the consistent rate of positive and negative types in bidirextional ABO incompatible group was 20%, the no-consistent rate was 80%.</p><p><b>CONCLUSION</b>After ABO-incompatible allo-HSCT, blood group antgen of patients shifts to the blood group of donors, there is a significant difference in the serological indicators between the minor and bidireetional ABO-incompatible patients and normal people.</p>
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Donneurs de tissus
/
Transplantation homologue
/
Incompatibilité sanguine
/
Transfusion sanguine
/
Système ABO de groupes sanguins
/
Transplantation de cellules souches hématopoïétiques
Type d'étude:
Prognostic_studies
Limites du sujet:
Humans
langue:
Zh
Texte intégral:
Journal of Experimental Hematology
Année:
2016
Type:
Article