Pathogenesis and Prevention of Transfusion-Associated Graft-versus-Host Disease / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1774-1779, 2015.
Article
Dans Chinois
| WPRIM
| ID: wpr-272523
ABSTRACT
Transfusion-associated graft-versus-host disease (TA-GVHD) is a rare complication of blood transfusion. The disease is fulminant and fatal in most patients. TA-GVHD is caused by transfused alloreactive donor T lymphocytes that attack host tissue, including skin, liver, gastrointestinal tract and bone marrow. Most patients are immunocompromised, but immunocompetent patients can also be involved. Irradiation of blood components is generally recommended to prevent the onset of TA-GVHD for susceptible recipients. This review focus on pathogenesis and prevention of TA-GVHD.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Donneurs de tissus
/
Transfusion sanguine
/
Moelle osseuse
/
Lymphocytes T
/
Tube digestif
/
Maladie du greffon contre l'hôte
/
Foie
Type d'étude:
Etude d'étiologie
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Journal of Experimental Hematology
Année:
2015
Type:
Article
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