Sustained-hypoxemia: a significant risk factor for anastomotic cicatricial stenosis after esophagectomy / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 28-31, 2008.
Article
Dans Chinois
| WPRIM
| ID: wpr-273895
ABSTRACT
<p><b>OBJECTIVE</b>To analyze retrospectively the roles of different factors, especially the factors in the anastomotic cicatricial, stenosis after esophagectomy.</p><p><b>METHODS</b>The clinical data of 1111 patients, undergone esophagectomy with immediate reconstruction for cancer in the Sun Yat-sen Cancer Center from December 1997 to December 2003, were analyzed retrospectively. Up to 19 factors were evaluated by univariate and multivariate Logistic regression analysis with SPSS 11.5 for windows. Spearman rank correlation was used to evaluate the factors that were statistically significant in Logistic regression analysis.</p><p><b>RESULTS</b>The overall incidence of anastomotic cicatricial stenosis was 6.84%. By using univariate Logistic regression, sustained-hypoxemia (P=0.003), chest complications (P=0.000), anastomotic leakage (P=0.000), a history of diabetes (P=0.019), a history of chronic obstructive pulmonary disease (P=0.046) and cardiovascular complications (P=0.015) came out to be significantly related to anastomotic stenosis. Multivariate Logistic regression showed that sustained-hypoxemia (P=0.044), chest complications (P=0.009), anastomotic leakage (P=0.001) and a history of diabetes (P=0.036) were statistically significant. Spearman rank correlation estimation revealed that sustained-hypoxemia was positively correlated with chest complications (r=0.105) and anastomotic leakage,(r=0.106), and chest complications were positively correlated with anastomotic leakage (r=0.228).</p><p><b>CONCLUSION</b>Sustained-hypoxemia is one of the significant factors for anastomotic cicatricial stenosis after esophagectomy.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Complications postopératoires
/
Pronostic
/
Chirurgie générale
/
Anastomose chirurgicale
/
Modèles logistiques
/
Études rétrospectives
/
Facteurs de risque
/
Oesophagectomie
/
Sténose de l'oesophage
/
Oesophage
Type d'étude:
Etude d'étiologie
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Chinese Journal of Gastrointestinal Surgery
Année:
2008
Type:
Article
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