Angioedema and systemic lupus erythematosus--a complementary association?
Annals of the Academy of Medicine, Singapore
;
: 142-145, 2007.
Article
Dans Anglais
| WPRIM
| ID: wpr-275216
ABSTRACT
<p><b>INTRODUCTION</b>We report angioedema as a rare presentation leading to a diagnosis of systemic lupus erythematosus (SLE).</p><p><b>CLINICAL PICTURE</b>A diagnosis of angioedema was delayed in a patient presenting with limb and facial swelling until she developed acute upper airway compromise. After excluding allergic and hereditary angioedema, acquired angioedema (AAE) was suspected, possibly precipitated by respiratory tract infection. Associated clinical and laboratory features led to a diagnosis of SLE.</p><p><b>TREATMENT</b>Management proved challenging and included high dose steroids and immunosuppressants.</p><p><b>OUTCOME</b>The patient responded to treatment and remains in remission without recurrence of the angioedema.</p><p><b>CONCLUSION</b>AAE occurs due to the acquired deficiency of inhibitor of C1 component of complement (C1 INH). Lymphoproliferative disorders and anti-C1 INH antibodies are well-described associations. However, one should also consider the possibility of SLE.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Ventilation artificielle
/
Insuffisance respiratoire
/
Thérapeutique
/
Sang
/
Encéphale
/
Imagerie par résonance magnétique
/
Protéines inhibitrices de la fraction C1 du complément
/
Syndrome des anticorps antiphospholipides
/
Diagnostic
Type d'étude:
Etude diagnostique
Limites du sujet:
Femelle
/
Humains
langue:
Anglais
Texte intégral:
Annals of the Academy of Medicine, Singapore
Année:
2007
Type:
Article
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