Studies on the chemical constituents in herb of Ranunculus sceleratus / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To isolate and determine the chemical constituents from Ranunculus sceleratus.</p><p><b>METHOD</b>Six compounds were isolated and purified by extraction and different kinds of column chromatography. The structures were determined on the basis of extensive spectral analysis such as EI-MS, 1H-NMR, 13C-NMR, DEPT and NOEDS.</p><p><b>RESULT</b>The structures were elucidated as stigmasta-4-ene-3,6-dione I, stigmasterol II, isoscopoletin III, scoparone IV, protocatechuic aldehyde V and protocatechuic acid VI, respectively.</p><p><b>CONCLUSION</b>Compound I, III, IV, V and VI were isolated from R. genus for the first time.</p>