Advances in the Urinary Exosomes in Renal Diseases / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 464-469, 2016.
Article
Dans Anglais
| WPRIM
| ID: wpr-277955
ABSTRACT
Cells secrete around 30- 100 nm membrane-enclosed vesicles that are released into the extracellular spaceis termed exosomes(EXs). EXs widely present in body fluids and incorporated proteins,nucleic acids that reflect the physiological state of their cells of origin and they may play an important role in cell-to-cell communication in various physiological and disease processes. In this article we review the recent basic and clinical studies in urinary EXs in renal diseases,focusing on their biological characteristics and potential roles as new biological markers,intervention treatment goals,and targeted therapy vectors in renal diseases.However,some issues still exist;in particular,the clinical application of EXs as a liquid biopsy technique warrants further investigations.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Urine
/
Marqueurs biologiques
/
Communication cellulaire
/
Diagnostic
/
Exosomes
/
Maladies du rein
Type d'étude:
Etude diagnostique
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Acta Academiae Medicinae Sinicae
Année:
2016
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS