Studies on dissolution rate in vitro of silymarin dropping pill / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To test the dissolution rate of silymarin dropping pill as well as to be compared with other three commercial products of the silymarin.</p><p><b>METHOD</b>By UV spectrophotometry, we studied the dissolution conditions of silymarin dropping pill and compared its dissolution rate with Yiganling tablets (film-coating, sugar-coating) and Legalon capsule which are available in the market.</p><p><b>RESULT</b>The dissolution parameters T50 and Td of silymarin dropping pill, Yiganling tablet (film-coating), Yiganling tablet (sugar-coating) and Legalon capsule are 6.78, 9.85 min, 51.01, 73.78 min, 74.35, 86.97 min and 53.10, 72.65 min.</p><p><b>CONCLUSION</b>The dissolution rate of silymarin dropping pill is superior to that of two kinds of Yiganling tablets and Legalon capsule.</p>