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A new isoindole alkaloid from leaves of Cassia siamea / 中国中药杂志
Zhongguo Zhong Yao Za Zhi ; (24): 1646-1648, 2016.
Article de Zh | WPRIM | ID: wpr-279193
Bibliothèque responsable: WPRO
ABSTRACT
A new isoindole alkaloid (1), has been isolated from the leaves of Cassia siamea by using various chromatographic techniques. Compound 1 is a new compound, determined as 5-(hydroxymethyl)-2-methyl-6-prenylisoindolin-1-one, and it displayed cytotoxicity against NB4, A549, SHSY5Y, PC3 and MCF7 cell lines with IC₅₀ values of 3.2,4.6,2.8,6.4, 2.5 μmol•L⁻¹, respectively.
Mots clés
Texte intégral: 1 Indice: WPRIM langue: Zh Texte intégral: Zhongguo Zhong Yao Za Zhi Année: 2016 Type: Article
Texte intégral: 1 Indice: WPRIM langue: Zh Texte intégral: Zhongguo Zhong Yao Za Zhi Année: 2016 Type: Article